Hunnivirus A

The
Picornavirus
Pages

Child level

Same level

Hunnivirus A is a species in the genus Hunnivirus. Hunnivirus A originally comprised of two picornaviruses which were identified in apparently healthy domestic young cattle (Bos taurus) and sheep (Ovis aries) in Hungary during 2008-2009 (Reuter et al., 2012). The name was changed in July 2013 from "hungarovirus" at the request of the ICTV Executive Committee. The name, Hunnivirus, is derived from Hungary and Northern Ireland where the first three hunniviruses were found. Complete genome sequencing and comparative analysis showed that these two viruses are related to each other and have a similar genome organization. At least 12 genotypes (HuV-A1 to A12) have now been described, including hunniviruses found in rats in Vietnam (Van Dung et al., unpub.) and a hunnivirus from a pangolin in China (Yang et al., 2020).

Genome orgranisation:

VPg+5′UTR^IRES-II[L/1A-1B-1C-1D-2A^npgp/2B-2C/3A-3B^VPg-3C^pro-3D^pol]3′UTR-poly(A)

References

Nguyen, D.V., Lu, L., Cuong, N.V., Tue, N.T., Hoa, N.T., Campbell, J., Hien, V.B., Bryant, J.E., Carrique-Mas, J., Baker, S., Woolhouse, M.E. and Simmonds, P. Detection and characterization of kobuviruses, cardioviruses and hunniviruses in Vietnamese rodents and civets. Unpublished.

Reuter, G., Pankovics, P., Knowles, N.J. and Boros, Á. (2012). Two closely related novel picornaviruses in cattle and sheep in Hungary from 2008 to 2009, proposed as members of a new genus in the family Picornaviridae. J. Virol. 86: 13295-13302. Epub 2012 Sep 26.

Van Dung, N., Lu, L., Van Cuong, N., Tue, N.T., Hoa, N.T., Campbell, J., Hien, V.B., Bryant, J.E., Carrique-Mas, J., Baker, S., Woolhouse, M.E. and Simmonds, P. Detection and characterization of kobuviruses, cardioviruses and hunniviruses in Vietnamese rodents and civets. Unpublished.

Yang S, Shan T, Xiao Y, Zhang H, Wang X, Shen Q, Wang Y, Yao Y, Liu Q, Wang H, Zhang W. Digging metagenomic data of pangolins revealed SARS-CoV-2 related viruses and other significant viruses. J Med Virol. 2020 Sep 17. doi: 10.1002/jmv.26524. Epub ahead of print. PMID: 32940906.