Mosavirus A

The
Picornavirus
Pages

Child level

Same level

Mosavirus A is a species in the genus Mosavirus. Mosavirus stands for mouse stool-associated picornavirus.

A novel picornavirus (designation M-7) found in the faeces of a canyon mouse (Peromyscus crinitus) in the USA in 2010 (JF973687; Phan et al., 2011).

A second mosavirus has been found in the faeces of an Afro-Palearctic migrant bird, the European roller (Coracias garrulus) (KF958461; Reuter et al., 2014).

Mosaviruses appear to encode two VPg's:

MoV-A1
GPYCGTCRQKKPVLKKAVTE (VPg1)
||| | ||| ||
GPYTGIVKKAPKKLKKVVTQ (VPg2)

MoV-A2
GPYCGACKRKAPVLKKTVAE (VPg1)
||| | ||| |
GPYSGMPRATPKKLKKVVVQ (VPg2)

Genome organisation:

VPg+5'UTR^IRES-II[L^pro/1A-1B-1C-1D-2A^npgp/2B-2C/3A-3B1^VPg1-3B2^VPg2-3C^pro-3D^pol]3'UTR-poly(A)

References

Phan, T.G., Kapusinszky, B., Wang, C., Rose, R.K., Lipton, H.L. and Delwart, E.L. (2011). The fecal viral flora of wild rodents. PLoS Pathog 7(9): e1002218. doi:10.1371/journal.ppat.1002218.

Reuter, G., Boros, Á., Kiss, T., Delwart, E. and Pankovics, P. (2014). Complete genome characterization of mosavirus (family Picornaviridae) identified in dropping of European roller (Coracias garrulus) in Hungary. Arch. Virol. 159: 2723-2729.