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 Cardiovirus

Child level

Cardiovirus A
Cardiovirus B
Cardiovirus C
"Cardiovirus D"
"Cardiovirus E"
"Cardiovirus F"
Genet fecal theilovirus
Goat cardiovirus
Guinea pig cardiovirus
Marmot cardiovirus

Same level

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Ailurivirus
Aphthovirus
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Cardiovirus
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"Mupivirus"
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Teschovirus
Torchivirus
Tottorivirus
Unassigned SG-1
 

The genus Cardiovirus consists three species, Cardiovirus A (formerly named Encephalomyocarditis virus), Cardiovirus B (formerly named Theilovirus) and Cardiovirus C. Cardiovirus A is comprised of two serotypes of encephalomyocarditis virus (EMCV). Cardiovirus B is comprised of Theiler's murine encephalomyelitis virus (TMEV), Vilyuisk human encephalomyelitis virus (VHEV), Thera virus (TRV;  isolated from rats). Cardiovirus C is comprised of Boone cardiovirus 1 and 2. There are three proposed new species: "Cardiovirus D" (Saffold virus), "Cardiovirus E" (red-backed vole cardiovirus) and "Cardiovirus F" (grey-backed vole cardiovirus). Note: due to the lack of complete polyprotein-coding sequences for genet fecal theilovirus and marmot cardiovirus, the original proposals as new species were rejected by the ICTV.

The cardioviruses are most closely related to members of the genera , Aphthovirus, Cosavirus, Erbovirus and Senecavirus.

Search for Cardiovirus sequences on GenBank

Genome organisation:

VPg+5’UTRIRES-II[L/1A-1B-1C-1D-2Anpgp/2B-2C/3A-3BVPg-3Cpro-3Dpol]3’UTR-poly(A)

Below: Phylogenetic analysis of the P1 capsid-coding region of the cardioviruses.

Key:
EMCV, encephalomyocarditis virus
SAFV, Saffold virus
TMEV, Theiler's murine encephalomyelitis virus
TRV, Thera virus
VHEV, Vilyuisk human encephalomyelitis virus

Software: MEGA 4.0
No. of Taxa : 46
Data File : ThV-EMCV-P1.meg
Data Title : Cardiovirus P1
Data Type : Nucleotide (Coding)
Analysis : Phylogeny reconstruction
Tree Inference : ==============================
->Method : Neighbor-Joining
->Phylogeny Test and options : Bootstrap (1000 replicates; seed=64238)
Include Sites : ==============================
->Gaps/Missing Data : Pairwise Deletion
->Codon Positions : 1st+2nd+3rd+Noncoding
Substitution Model : ==============================
->Model : Nucleotide: Maximum Composite Likelihood
->Substitutions to Include : d: Transitions + Transversions
->Pattern among Lineages : Same (Homogeneous)
->Rates among sites : Uniform rates
No. of Sites : 2610
No Of Bootstrap Reps = 1000

 

 

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