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 Cardiovirus B

Child level

Theiler's MEV
Vilyuisk HEV
Cardiovirus B3
Thera virus
Cardiovirus B

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The species Cardiovirus B (formerly named Theilovirus) consists of 16 genotypically different viruses (which may also be distinct serotypes): Theiler's murine encephalomyelitis virus (TMEV), Vilyuisk human encephalomyelitis virus (VHEV), Thera virus (TRV), Saffold virus (SAFV) 1, SAFV-2, SAFV-3, SAFV-4, SAFV-5, SAFV-6, SAFV-7, SAFV-8, SAFV-9, SAFV-10 and SAFV-11, Genet fecal theilovirus (GFTV) and rat cardiovirus 1 (RCV-1).

The recently determined complete genome sequence of Sikhote-Alin virus (Alkhovsky et al., unpub.) suggests that it is a TMEV isolate.

Search of Cardiovirus B sequences on GenBank

TMEV in guinea pigs? - Hansen et al., 1997.

Two partial 3D sequences have been reported from laboratory mice (Mus musculus) in India (Sircar et al., unpub.): M21/India/2017 (MF508653) and M23/India/2017 (MF508654) both share 99% aa identity with Sikhote-Alin virus and Vilyuisk human encephalomyelitis virus.

References

Hansen, A.K., Thomsen, P. and Jensen, H.J. (1997). A serological indication of the existence of a guineapig poliovirus. Lab. Anim. 31: 212-218.

 

 

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