The
Picornavirus
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Child level |
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Same level |
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| There are two major differences between
porcine kobuvirus 1 (PKV-1) and the other kobuviruses; 1) PKV-1 possesses a type IV IRES, while the others
have a type II IRES; 2) within the 2B region, PKV-1 encodes two copies
of a 30-amino-acid (90-nucleotide)-long motif,
AANRVAESIETTAS(/T)V(/A)VREADLARSTLNISM, one after the other (in
tandem), which extends the 2B region (to 585 instead of 495
nucleotide in U1 or Aichi virus). Van den Brand et al. (2011) have detected the genome of porcine kobuvirus in a faecal swab obtained from a pine marten (Martes martes). References Reuter, G., Boldizsár, Á., Kiss, I. and Pankovics, P. (2008). Candidate new species of kobuvirus in porcine hosts [letter]. Emerg. Infect. Dis. 14: 1968-1970. doi: 10.3201/eid1412.080797. Reuter, G., Boldizsár, A. and Pankovics, P. (2009). Complete nucleotide and amino acid sequences and genetic organization of porcine kobuvirus, a member of a new species in the genus Kobuvirus, family Picornaviridae. Arch Virol. 154: 101-108. 2008 Dec 19 [Epub ahead of print]; doi: 10.1007/s00705-008-0288-2. van den Brand, J.M., van Leeuwen, M., Schapendonk, C.M., Simon, J.H., Haagmans, B.L., Osterhaus, A.D. and Smits, S.L. (2011). Metagenomic analysis of the viral flora of pine marten and European badger feces. J. Virol. 2011 Dec 14. [Epub ahead of print]. Yu, J.-M., Jin, M., Zhang, Q., Li, H.-Y., Li, D.-D., Xu, Z.-Q., Li, J.-S., Cui, S.-X., Yang, S.-H., Liu, N. and Duan, Z.-J. (2009). Candidate porcine Kobuvirus, China. Emerg Infect Dis. 15: 823-825. Yu, J.-M., Xu, Z.-Q., Li, B.W., Zhang, Q., Cui, S.-X., Jin, M. and Duan, Z.-J. (2011). Analysis and characterization of the complete genome of a member of a new species of kobuvirus associated with swine. Arch Virol. 156: 747-751. 2011 Jan 28. [Epub ahead of print]. |