Sicinivirus A

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Picornavirus
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Sicinivirus A is a new species in the new genus, Sicinivirus.

Sicinivirus 1 is a new picornavirus detected in chickens in the Republic of Ireland. Sicini is the Gaelic word for chickens. Sicinivirus 1 is most closely related to passerivirus A1 (formerly turdivirus 1) having amino acid identities of 30.5%, 38.1% and 46.8% in the P1, P2 and P3 polypeptides, respectively.

The genome sequences of two picornaviruses (designated chicken picornavirus 1 by the authors) are most closely related to Sicinivirus 1 (Lau et al., 2014).

The siciniviruses fall into 5 genetic groups (types) based on comparisons of their VP1 sequences (N.J. Knowles, unpublished data).

Genome organisation:

VPg+5'UTR^IRES-II[L/1AB-1C-1D/2A-2B-2C/3A-3B^VPg-3C^pro-3D^pol]3'UTR-poly(A)

References

Bullman, S., Kearney, K., O'Mahony, M., Kelly, L., Whyte, P., Fanning, S. and Morgan, J.G. (2014). Identification and genetic characterisation of a novel picornavirus from chickens. J. Gen. Virol. 95: 1094-1103.

Lau, S.K., Woo, P.C., Yip, C.C., Li, K.S., Fan, R.Y., Bai, R., Huang, Y., Chan, K.H. and Yuen, K.Y. (2014). Chickens host diverse picornaviruses originated from potential interspecies transmission with recombination. J. Gen. Virol. 95: 1929-1944.