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The genus Kobuvirus consists of three species,
Aichivirus A
(formerly Aichi virus),
Aichivirus B
(formerly Bovine kobuvirus) and
Aichivirus C.
The species
Aichivirus A
consists of four types:
Aichi virus 1,
canine kobuvirus 1,
feline kobuvirus 1 and
murine kobuvirus 1.
The species
Aichivirus B
consists of three types:
bovine kobuvirus 1,
ferret kobuvirus 1 &
ovine kobuvirus 1.
The species
Aichivirus C consists of a single type:
porcine kobuvirus 1.
Caprine kobuvirus,
cattle kobuvirus and
European roller kobuvirus may represent three further candidate
species.
Other kobu-like viruses have been identified in
bats and
rabbits.
Search for Kobuvirus
sequences on GenBank
Genome organisation
Aichivirus A (Aichi virus 1, canine kobuvirus 1,
feline kobuvirus 1 & murine kobuvirus
1):
VPg+5'UTRIRES-V[L/1AB-1C-1D/2AH-Box/NC-2B-2C/3A-3BVPg-3Cpro-3Dpol]3'UTR-poly(A)
Aichivirus B (bovine kobuvirus 1, ferret
kobuvirus 1 & ovine kobuvirus 1):
VPg+5'UTRIRES-V[L/1AB-1C-1D/2AH-Box/NC-2B-2C/3A-3BVPg-3Cpro-3Dpol]3'UTR-poly(A)
Aichivirus C (porcine kobuvirus 1):
VPg+5'UTRIRES-IV[L/1AB-1C-1D/2AH-Box/NC-2B-2C/3A-3BVPg-3Cpro-3Dpol]3'UTR-poly(A)
3A polypeptide
Recently, Greninger et al. (2012) have report that the N-terminal
glycines of Aichi virus, bovine kobuvirus and human salivirus (klassevirus)
are myristoylated despite not having an N-terminal canonical myristoylation motif (GxxxT/S).
References
Greninger, A.L., Knudsen, G.M., Betegon, M., Burlingame, A.L. and Derisi,
J.L. (2012). The 3A protein from multiple picornaviruses utilizes the
golgi adaptor protein ACBD3 to recruit PI4KIIIβ. J Virol. 86: 3605-3616.
Epub 2012 Jan 18.
Current taxonomy
| Genus:
Kobuvirus |
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Species: Aichivirus
A
(4 types) |
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type: Aichi virus 1 |
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type: feline
kobuvirus 1 |
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type: canine kobuvirus 1 |
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type: murine kobuvirus 1 |
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Species:
Aichivirus B
(3 types) |
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type: bovine kobuvirus 1 |
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type: ferret
kobuvirus 1 |
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type: sheep
kobuvirus 1 |
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Species:
Aichivirus C (1 type) |
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type: porcine kobuvirus 1 |
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unassigned: caprine
kobuvirus 1 |
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unassigned: cattle kobuvirus 1 & 2 |
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unassigned: European
roller kobuvirus 1 |
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