The
Picornavirus
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Child level |
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Genera |
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Avihepatovirus A (formerly named Duck hepatitis A virus) is a single species
in the genus Avihepatovirus. The only
member of Avihepatovirus A, duck
hepatitis A virus (DHAV), consists of three genotypes, DHAV-1, DHAV-2
and DHAV-3. DHAV-2 and DHAV-3 are both serologically distinct from
DHAV-1, but have never been compared with each other. The complete
genome sequences of DHAV-1, DHAV-2 and DHAV-3 were first reported by
Kim et al. (2006),
Tseng & Tsai (2007) and
Kim et al. (2007a,b), respectively. Ding and Zhang (2007) have suggested that DHAV-1 has a short leader polypeptide (30 aa) with a L/G cleavage site between it and VP0. This would result in a myristoylation motif at the N-terminus of VP0 (GxxxS). These sequences are also conserved in DHAV-2 and DHAV-3. DHAV-3 has been shown to be the cause of a newly described disease, goose haemorrhagic hepatitis, in China (Liu et al., 2011; JF835025). Previously, DHAV-1 was named duck hepatitis virus I (DHV-I) and along with DHV-II and DHV-III were considered unclassified picornaviruses causing duck virus hepatitis. Subsequencly, DHV-II and DHV-III were identified as astroviruses. |
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| Search for Duck hepatitis A virus sequences on GenBank | |
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References Ding, C. and Zhang, D. (2007). Molecular analysis of duck hepatitis virus type 1. Virology 361: 9-17. Kim, M.-C., Kwon, Y.-K., Joh, S.-J., Lindberg, A.M., Kwon, J.-H., Kim, J.-H. and Kim, S.-J. (2006). Molecular analysis of duck hepatitis virus type 1 reveals a novel lineage close to the genus Parechovirus in the family Picornaviridae. J. Gen. Virol. 87: 3307-3316. Kim, M.C., Kwon, Y.K., Joh, S.J., Kwon, J.H., Kim, J.H. and Kim, S.J. (2007a). Development of one-step reverse transcriptase-polymerase chain reaction to detect duck hepatitis virus type 1. Avian Dis. 51: 540-545. Kim, M.C., Kwon, Y.K., Joh, S.J., Kim, S.J., Tolf, C., Kim, J.H., Sung, H.W., Lindberg, A.M. and Kwon, J.H. (2007b). Recent Korean isolates of duck hepatitis virus reveal the presence of a new geno- and serotype when compared to duck hepatitis virus type 1 type strains. Arch. Virol. 152: 2059-2072. Liu, M., Fanyi-Meng, Li, X.J., Zhang, Z., Liu, S. and Zhang, Y. (2011). Goose haemorrhagic hepatitis caused by a new subtype duck hepatitis type 1 virus. Vet. Microbiol. 152: 280-283. Tseng, C.-H. and Tsai, H.-J., (2007). Molecular characterization of a new serotype of duck hepatitis virus, Virus Res. 126: 19-31.
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