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The species Cardiovirus B
(formerly named Theilovirus) consists of 16 genotypically different viruses (which may also be distinct serotypes): Theiler's murine encephalomyelitis virus (TMEV),
Vilyuisk human encephalomyelitis virus
(VHEV), Thera virus (TRV), Saffold virus (SAFV) 1, SAFV-2, SAFV-3,
SAFV-4, SAFV-5, SAFV-6, SAFV-7, SAFV-8, SAFV-9, SAFV-10 and SAFV-11,
Genet fecal theilovirus (GFTV) and
rat cardiovirus 1 (RCV-1).
The recently determined complete genome
sequence of Sikhote-Alin virus (Alkhovsky
et al.,
unpub.) suggests that it is
a TMEV isolate.
Search of Cardiovirus B sequences on GenBank
TMEV in
guinea pigs? - Hansen et al., 1997.
Two partial 3D sequences have been
reported from laboratory mice (Mus musculus) in India (Sircar
et al., unpub.): M21/India/2017 (MF508653)
and M23/India/2017 (MF508654)
both share 99% aa identity with Sikhote-Alin virus and Vilyuisk human
encephalomyelitis virus.
References
Hansen, A.K., Thomsen, P. and Jensen,
H.J. (1997). A serological indication of the existence of a guineapig
poliovirus. Lab. Anim. 31: 212-218.
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