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 Cardiovirus theileri

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The species Cardiovirus theileri (formerly Cardiovirus B and before that Theilovirus) consists of five genotypically different viruses (which may also be distinct serotypes): Theiler's murine encephalomyelitis virus (TMEV), Vilyuisk human encephalomyelitis virus (VHEV), Thera virus (TRV), Genet fecal theilovirus (GFTV) and rat cardiovirus 1 (RCV-1).

The complete genome sequence of Sikhote-Alin virus (Alkhovsky et al., unpub.) suggests that it is a TMEV isolate.

The capsid-coding region of a genome sequence of a virus from a mouse (Mus musculus) in China (OQ715975) suggests that is closely related to VHEV (Chen et al., 2023).

Search of Cardiovirus theileri sequences on GenBank

TMEV in guinea pigs? - Hansen et al., 1997.

Two partial 3D sequences have been reported from laboratory mice (Mus musculus) in India (Sircar et al., unpub.): M21/India/2017 (MF508653) and M23/India/2017 (MF508654) both share 99% aa identity with Sikhote-Alin virus and Vilyuisk human encephalomyelitis virus.

References

Chen YM, Hu SJ, Lin XD, Tian JH, Lv JX, Wang MR, Luo XQ, Pei YY, Hu RX, Song ZG, Holmes EC, Zhang YZ. Host traits shape virome composition and virus transmission in wild small mammals. Cell. 2023 Oct 12;186(21):4662-4675.e12. doi: 10.1016/j.cell.2023.08.029. Epub 2023 Sep 20. PMID: 37734372.

Hansen, A.K., Thomsen, P. and Jensen, H.J. (1997). A serological indication of the existence of a guineapig poliovirus. Lab. Anim. 31: 212-218.

 

 

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