CVA Prototypes

Enterovirus species	Serotype	Strain	Origin	Year	Illness	Source	Reference
Enterovirus C	CVA1	Tompkins	Coxsackie, N.Y.	1947	Paralytic illness	stools	Dalldorf et al., 1949
Enterovirus A	CVA2	Fleetwood	Delaware	1947	Paralytic illness	stools	Sickles and Dalldorf, 1949
Enterovirus A	CVA3	Olson	New York	1948	Aseptic meningitis	stools	Sickles and Dalldorf, 1949
Enterovirus A	CVA4	High Point	North Carolina	1950	--	sewage from a polio community	Melnick, 1950
Enterovirus A	CVA5	Swartz	New York	1950	Poliomyelitis	stools	Dalldorf and Sickles, 1953
Enterovirus A	CVA6	Gdula	New York	1949	Aseptic meningitis	stools	Dalldorf et al., 1949
Enterovirus A	CVA7	Parker	New York	1949	Aseptic meningitis	stools	Dalldorf et al., 1949
Enterovirus A	CVA8	Donovan	New York	1949	Poliomyelitis	stools	Dalldorf et al., 1949
Enterovirus B	CVA9	Bozek	New York	1950	Aseptic meningitis	stools	Dalldorf et al., 1949
Enterovirus A	CVA10	Kowalik	New York	1950	Aseptic meningitis	stools	Dalldorf et al., 1949
Enterovirus C	CVA11	Belgium-1	Belgium	1951	Epidemic myalgia	stools	Curnen
Enterovirus A	CVA12	Texas-12	Texas	1948	--	flies from a polio community	Melnick, 1950
Enterovirus C	CVA13	Flores	Mexico	1952	none	stools	Sickles
Enterovirus A	CVA14	G-14	South Africa	1950	none	stools	Gear
Enterovirus C	CVA15	G-9	South Africa	1950	none	stools	Gear
Enterovirus A	CVA16	G-10	South Africa	1951	none	stools	Gear
Enterovirus C	CVA17	G-12	South Africa	1951	none	stools	Gear
Enterovirus C	CVA18	G-13	South Africa	1950	none	stools	Gear
Enterovirus C	CVA19	NIH-8663 (Dohi)	Japan	1952	Guillain-Barre syndrome	stools	Huebner
Enterovirus C	CVA20	IH-35	New York	1955	Infectious hepatitis	stools	Sickles
Enterovirus C	CVA20a	Tulane	Louisiana	1951	Poliomyelitis?	stools	Sickles et al., 1959
Enterovirus C	CVA20b	Cecil	South Africa	1951	none	stools	Sickles et al., 1959
Enterovirus C	CVA20c	Thai C-18	Thailand	1958/9?	Cholera	stools	Abraham and Cheever, 1963
Enterovirus C	CVA21	Kuykendall	California	1952	Poliomyelitis	stools	Lennette
Enterovirus C	CVA21(V)	Coe	?	?	Mild respiratory disease	throat washings	Lennette et al., 1958
Enterovirus C	CVA22	Chulman	New York	1955	Vomiting and diarrhea	stools	Sickles
-	CVA23	= echovirus 9
Enterovirus C	CVA24	Joseph	South Africa	1952	none	stools	Gear
Enterovirus C	CVA24'	DN-19	Texas	1963	Infantile diarrhea	stools	?
Enterovirus C	CVA24(V)	EH 24/70	Singapore	1970	AHC	conjunctival scrapings	Mirkovic et al., 1974
All prototypes were isolated from stools except type 4 (sewage from a polio community); type 12 (flies from a polio community); type 21/Coe (throat washings); and type 24/EH 24/70 (conjunctival scrapings). V = variant AHC = acute haemorrhagic conjuncivitis

References

Dalldorf et al., 1949 (J. exp. Med. 89: 567)

Sickles and Dalldorf, 1949 (Proc. Soc. exp. Biol. Med. 72: 30)

Dalldorf and Sickles, 1953 (In: Diagnostic Procedures for Virus and Rickettsial Diseases 2nd Edition. Am. Public Health Assoc., New York, p.153)

Melnick, 1950 (Bull. N.Y. Acad. Med. 26: 342)

Curnen

Sickles

Gear

Huebner

Lennette

Lennette et al., 1958 (Am. J. Hyg. 68: 272)

Mirkovic et al., 1974 (Intervirol. 4: 119-127)

Sickles et al., 1959 (Proc. Soc. exp. Biol. Med. 102: 742-743)

Abraham and Cheever, 1963. (PSEBM 112: 981)