EV-C Prototypes

To be updated...

Serotype	Strain	Origin	Year	Illness	Source	Reference
PV1	Brunhilde	Maryland	1939	Paralytic polio	Faeces	Howe and Bodian, 1941; Bodian et al., 1949
PV1	Mahoney	Ohio	1941	none	Faeces	see ATCC catalogue
PV2	Lansing	Michigan	1937	Fatal paralytic polio	Brain tissue	Kessel et al., 1946
PV3	Leon	California	1937	Fatal paralytic polio	Spinal cord	Armstrong, 1939; ?
CVA1	Tompkins	Coxsackie, N.Y.	1947	Paralytic illness	stools	Dalldorf et al., 1949
CVA11	Belgium-1	Belgium	1951	Epidemic myalgia	stools	Curnen
CVA13	Flores	Mexico	1952	none	stools	Sickles
CVA17	G-12	South Africa	1951	none	stools	Gear
CVA19	NIH-8663 (Dohi)	Japan	1952	Guillain-Barre syndrome	stools	Huebner
CVA20	IH-35	New York	1955	Infectious hepatitis	stools	Sickles
CVA20a	Tulane	Louisiana	1951	Poliomyelitis?	stools	Sickles et al., 1959
CVA20b	Cecil	South Africa	1951	none	stools	Sickles et al., 1959
CVA20c	Thai C-18	Thailand	1958/9?	Cholera	stools	Abraham and Cheever, 1963
CVA21	Kuykendall	California	1952	Poliomyelitis	stools	Lennette
CVA21(V)	Coe	?	?	Mild respiratory disease	throat washings	Lennette et al., 1958
CVA22	Chulman	New York	1955	Vomiting and diarrhoea	stools	Sickles
CVA24	Joseph	South Africa	1952	none	stools	Gear
CVA24'	DN-19	Texas	1963	Infantile diarrhoea	stools	?
CVA24(V)	EH 24/70	Singapore	1970	AHC	conjunctival scrapings	Mirkovic et al., 1974
EV-C95
EV-C96
EV-C99
EV-C102
EV-C104
EV-C105
EV-C109
EV-C113
EV-C116	126
EV-C117	LIT22				nasopharyngeal swab	Daleno, Esposito & Principi, unpub.
EV-C118	ISR10					Daleno et al., unpub.

All prototypes were isolated from stools CV-21/Coe (throat washings); and CV-24/EH 24/70 (conjunctival scrapings). V = variant AHC = acute haemorrhagic conjunctivitis The former serotype CVA15 has been reclassified as a strain of CVA11 and similarly CVA18 is now belongs to CVA13.

References

Howe and Bodian, 1941 (Bull. J. Hopk. Hosp. 69: 149)

Bodian et al., 1949 (Am. J. Hyg. 49: 234)

Armstrong, 1939 (Public Health Repts. 54: 1719, 2302

Kessel et al., 1946 (Am. J. Hyg. 43: 82)

Dalldorf et al., 1949 (J. exp. Med. 89: 567)

Sickles and Dalldorf, 1949 (Proc. Soc. exp. Biol. Med. 72: 30)

Dalldorf and Sickles, 1953 (In: Diagnostic Procedures for Virus and Rickettsial Diseases 2nd Edition. Am. Public Health Assoc., New York, p.153)

Melnick, 1950 (Bull. N.Y. Acad. Med. 26: 342)

Curnen

Sickles

Gear

Huebner

Lennette

Lennette et al., 1958 (Am. J. Hyg. 68: 272)

Mirkovic et al., 1974 (Intervirol. 4: 119-127)

Sickles et al., 1959 (Proc. Soc. exp. Biol. Med. 102: 742-743)

Abraham and Cheever, 1963. (PSEBM 112: 981)