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 Hepatovirus struct.

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VIPERdb - Virus Particle Explorer

Genus: Hepatovirus

  HAV 3Cpro  
   
Virus PDB no. Description [EMBL accession no.] Reference
HAV 1HAV 3C proteinase Allaire et al., 1994; Bergmann et al., 1997  
1QA7 Crystal complex of the 3C proteinase from hepatitis A virus with its inhibitor and implications for the polyprotein processing in HAV.
4QPI HAV capsid Wang et al., 2014
4QPG HAV capsid Wang et al., 2014
 

References

Allaire, M., Chernaia, M.M., Malcolm, B.A. and James, M.N. (1994). Picornaviral 3C cysteine proteinases have a fold similar to chymotrypsin-like serine proteinases. Nature 369: 72-76.

Bergmann, E.M., Mosimann, S.C., Chernaia, M.M., Malcolm, B.A. and James, M.N.G. (1997). The refined crystal structure of the 3C gene product from hepatitis-A virus: specific proteinase activity and RNA recognition. Journal of Virology 71: 2436-2448.

Wang, X., Ren, J., Gao, Q., Hu, Z., Sun, Y., Li, X., Rowlands, D.J., Yin, W., Wang, J., Stuart, D.I., Rao, Z. and Fry, E.E. (2014). Hepatitis A virus and the origins of picornaviruses. Nature 2014 Oct 19. doi: 10.1038/nature13806. [Epub ahead of print]. PubMed PMID: 25327248.

 
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